Question: What is mifepristone used for?

Mifeprex (mifepristone) is a drug that blocks a hormone called progesterone that is needed for a pregnancy to continue. Mifeprex, when used together with another medicine called misoprostol, is used to end an early pregnancy (70 days or less since the first day of the last menstrual period).

What does mifepristone do to a baby?

Mifepristone binds to progesterone receptors in the placenta and uterus and blocks progesterone from binding, preventing the normal effect of progesterone on the fetus.

Will I bleed after taking mifepristone?

Vaginal bleeding — similar to a menstrual period — will usually start 1 to 2 days after taking mifepristone, although some women may start bleeding earlier than this. In most cases, bleeding at this stage can be managed with regular sanitary pads.

When Should bleeding start after taking mifepristone?

For most people, the cramping and bleeding usually starts 1-4 hours after taking the misoprostol. Its normal to see large blood clots (up to the size of a lemon) or clumps of tissue when this is happening. Its kind of like having a really heavy, crampy period, and the process is very similar to an early miscarriage.

Can I take mifepristone and misoprostol at the same time orally?

Clinical studies have demonstrated that oral administration of mifepristone (RU 486) 600 mg, followed by the oral use of misoprostol 400 μg 36–48 hours later, results in a complete abortion rate of 87–96% at up to 49 days of gestation [1], [2], [3], [4].

How long does mifepristone stay in your blood?

Following a distribution phase, elimination of mifepristone is slow at first (50% eliminated between 12 and 72 hours) and then becomes more rapid with a terminal elimination half-life of 18 hours.

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